Kamis, 05 Mei 2011

[V720.Ebook] Ebook My Brain is Open: The Mathematical Journeys of Paul Erdos, by Bruce Schechter

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My Brain is Open: The Mathematical Journeys of Paul Erdos, by Bruce Schechter

A compelling portrait of the eccentric mathematical wayfarer, Paul Erds.

  • Sales Rank: #915493 in Books
  • Brand: Brand: Simon Schuster
  • Published on: 1998-09-10
  • Original language: English
  • Number of items: 1
  • Dimensions: 9.75" h x 6.50" w x 1.25" l,
  • Binding: Hardcover
  • 224 pages
Features
  • Used Book in Good Condition

Amazon.com Review
Physicist and science writer Bruce Schechter's biography of legendary Hungarian mathematician Paul Erd�s is an engaging portrait, warm and intimate, bringing this strange, happy man to life. Schechter's focus is quite a bit tighter, and more traditionally biographical, than Paul Hoffman's in The Man Who Loved Only Numbers. Here, we get to see Erd�s's brief childhood transform quickly into a carefree adolescence of solving difficult math problems with his circle of brilliant friends--uniquely encouraged by a country that valued the contributions of mathematics in a way that has never been equaled. Fleeing the Holocaust, Erd�s never settled down, instead traveling from place to place, showing up on the doorsteps of other mathematicians with his few possessions and an open mind. During his career, Erd�s published more papers than any other mathematician in history. Most of the papers were collaborations:

For Erd�s, the mathematics that consumed most of his waking hours was not a solitary pursuit but a social activity. One of the great mathematical discoveries of the twentieth century was the simple equation that two heads are better than one.... That radical transformation of how mathematics is created is the result of many factors, not the least of which was the infectious example set by Erd�s.

Schechter spoke with many of Erd�s's collaborators to complete this biography, which reveals the odd mathematician as charming, opinionated, and completely dependent upon the kindness of others. Schechter not only tells his fascinating story, but introduces some intriguing mathematics problems (with easy-to-understand explanations) to show readers why Erd�s loved the elegance of numbers more than anything else in the world. --Therese Littleton

From Publishers Weekly
Schechter's biography of mathematical wizard Paul Erdos, who died in 1996, follows closely on the publication of one by Paul Hoffman (The Man Who Loved Only Numbers, Forecasts, June 8). Curiously, both biographers were associated with Discover magazine?Schechter as a staff writer and Hoffman as editor-in-chief. Like Hoffman, Schechter adeptly portrays both the quirky Erdos and his daimon, the pure, abstract universe of numbers. Schechter's explanations of number theory are better suited than Hoffman's for readers not in technical or scientific professions. He doesn't delve into subjects like Ramsey theory in quite the detail that Hoffman does, and his digressions tend to be more relevant to Erdos's life. Hoffman, for example, goes into the story of Fermat's last theorem, which played almost no role in Erdos's career. And Schechter seems more evenhanded in his account of Erdos's controversial contribution to the solution of the Prime Number Theorem. Although Schechter didn't know Erdos personally, as Hoffman did, and although his account lacks some of the other's humanizing vignettes, readers will be engrossed by his well-crafted chronicle of the eccentric Hungarian and of the mathematical worlds he traversed for eight decades.
Copyright 1998 Reed Business Information, Inc.

From Library Journal
Perhaps the most prolific mathematician of the 20th century, Erdos lived a modest, itinerant life dedicated wholly to mathematics. This book provides a rewarding glimpse into his genius and eccentricity.
Copyright 1999 Reed Business Information, Inc.

Most helpful customer reviews

3 of 3 people found the following review helpful.
To prove and conjecture: great book about beautiful mind and sad life.
By Grettir Strong
Shurik, a friend of mine I used to share student dorm with, was a mathematician. Algebraist, to be precise. We talked a lot discussing multitude of topics, not necessarily mathematical ones. In those days hot water was customarily shut off across campus during summer season so students could prepare for exams without such a distraction as hot showers. That fact prompted me to comment that our lifestyle, while notably different, still somewhat resembles what a lifestyle in Upper Paleolithic might look like. Shurik was digesting my remark for a few moments with the stamp of intense thinking on his face (his Calculus test was next day), then said excitedly:

- Dude, you know why there was no hot water in Upper Paleolithic? That's because the water pressure was not strong enough in the Lower Paleolithic!

That insignificant episode from my student years characterizes true mathematicians very eloquently. They are quite unusual breed of humankind with extraordinary abilities to locate not very obvious properties and relations in seemingly regular objects and notions. Having been exposed to interaction with mathematicians for sometime I, by the time the book of Mr. Schechter was read through, felt I knew Paul Erdos almost personally. Very light and elegant writing style of the author was a contributing factor as well.

Mathematicians rarely can be aggressive. Usually, they are very sensitive and kind people. In this regard the portrait of Paul Erdos by Mr. Schechter goes along quite naturally with my experience of dealing with them. At the same time that portrait leaves a very sad impression of the true inner nature of Erdos - depressingly lonely person, with no family and no home. The deep tragedy of the Erdos family with Paul's siblings gone by disease, father's suffering in Russian exile, terrible WWII ordeals - all that makes you wonder how Paul and his parents can continue "to prove and conjecture" so successfully under such horrendous circumstances? Author partly explains this phenomenon very brightly describing the scientific and especially educational traditions in Hungary before the war. Indeed, the density of incredible talents generated in this small central European country somewhat shocking. It underscores how important the role of truly good teacher in elementary school can be. Taking into account all that and also the fact that both parents of Erdos were superior math teachers in high school themselves a reader can see the roots of the enormous productivity of Erdos, who published more math papers in multiple branches of it than any other scientist in history. But it also can be a city of Budapest whose streets, as per Mr. Schechter, are very inviting for any kind or scientific reasoning - although not a scientist myself, I did experience the same when I was roaming with friends along Duna shores in Buda one summer.

The mathematical content of the book is very engaging for non-mathematicians. It is explained almost with no formulas but Mr. Schechter manages to convey the depth of the mathematical ideas very well without them. It is especially applicable to the chapter about prime numbers. The primes, although endless in the set of integers, do have very strange properties. Take the theorem proved by Chebychev first and re-proved by Erdos by elementary means - between N and 2N there is always a prime. At the same time we know that the intervals without primes can be as long as one would wish. At first glance two facts seems to contradict to each other but they do not. Facts like that are abundant in the Numbers Theory with most enigmatic one as a problem of primes distribution and Riemann function. Mr. Schechter does a good job providing historical background of the Numbers Theory, its evolution, contributions of Paul Erdos and controversy of Erdos and Selberg.

I have to admit the author did a brilliant homework researching all kinds of details pertinent to mathematics and its origins. I did enjoy pages about clay table Plimpton 322 with its incredible content of Pythagorean triplets as well as multitude of other stories like most bizarre "application" of Numbers Theory when close collaborator of Erdos avoided deportation to Gulag just because he happened to have his publication on the subject in Russian mathematical magazine with him. In this regard, the book of Mr. Schechter can be considered as not so much as biography of Paul Erdos but as biography of mathematics as a scientific discipline. Humor, albeit sometimes very dark (for example, about math students, who were "studying" Jordan theorem being confined to "inner area", id est being imprisoned) sparking the text regularly and appropriately.

Mathematics is somewhat similar to soccer. While everybody can perceive the beauty of ball handling by say Riquelme or Robinho, very few of us can do the same on the soccer field. In math, formulation of the conjecture can be deceptively simple and elegant, and most of us can understand it well. At the same time, it is very different story once you start thinking about trying to prove that conjecture. In many cases it might require years of learning and tons of exercises. But even that no guarantee to success. The inclination to a special way of thinking is required. In this regard, magic of Riquelme on the stadium is direct equivalent of wizardry of Erdos in Numbers Theory. The books similar to Mr. Schechter facilitate our comprehension of the conjecture beyond mere formulation, opening the curtain after which the proof is hidden.

On the other note, I can't stop thinking of what kind of future European science might have should its development was not brutally aborted by sad realities of Second World War. True, many of bright Hungarian (and other) minds escaped from the inferno of warfare and extermination campaigns; true, many of them intensified their research in military related directions and achieved significant results. Still so many perished needlessly making a good number of famous European scientific centers empty and forgotten for a very long time. It seems incredible that one person's paranoia can mercilessly terminate so much in such a short period of time. Let's us hope the future Erdoses will never be forced to travel so intensively against their wills even with theirs brains open so widely.

33 of 34 people found the following review helpful.
Fascinating biography with lucid cameos of math. topics
By norton
This beautiful book is an intellectually rich biography of one of the world's most prolific mathematicians. Amusingly, inoffensively and highly idiosyncratic, Erdos worked on hard problems in apparently simple fields, taking rather easily explained concepts and forging powerful new results and tools with a speed which astounded professional colleagues. Bruce Schechter does a magnificent job of clearly explaining what Erdos did and the many connections between his work and other areas of mathematics and, more generally, science. Through frequent digressions he paints both a humane portrait of a uniquely caring individual and a thumbnail sketch of western political oppression around the world during the first sixty years of this century.
This book also will introduce readers, in a gentle and interesting manner, to the world of numbers and mathematics. The nature of prime numbers and how they are distributed, famous conjectures such as Goldbach's, topics in graph theory and combinatorial mathematics, and more are made accessible to the reader. The account of the controversy surrounding the "elementary" proof of the Prime Number Theorem benefits from the author's access to newly available material, and will be of interest to both laypeople and mathematicians. Other topics, introduced through natural association with the subject at hand, include Godel's Theorem, Russell's paradox, the Monty Hall problem (made famous by Marilyn vos Savant), the nature of infinity, proving theorems by contradiction, and the normal distribution.
Though Erdos is known to many for his unusual life style and behavior, this book does not dwell on the bizarre but weaves such facets of his life into the more exciting mathematical development of the person. This biography ranks among the very best of the numerous works about mathematicians which I have read over the past 45 years. Arguably, more has been written about Erdos in the past decade or two than about any other mathematician. Despite this, Schechter's new contribution is an outstanding addition to the literature

0 of 0 people found the following review helpful.
The Best of Math Biography
By Gerald Hawkins
It's a delicate balancing act when writing about genius, either giving way to a gossipy hero-worshiping mysticism or adhering so closely to the technical details that all but the those in that field are lost. This book succeeds in depicting the things that made Paul Erdos a publicly interesting figure, but also shows, rather then tells, how simple and brilliants his theorems and proofs could be. It's a quick read and difficult to resist trying variations on his graph theory problems!

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Sabtu, 30 April 2011

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  • Sales Rank: #1313737 in Books
  • Published on: 2016-08-15
  • Original language: English
  • Number of items: 1
  • Dimensions: 7.50" h x .75" w x 5.25" l, .0 pounds
  • Binding: Flexibound
  • 264 pages

Review
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About the Author
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Selasa, 26 April 2011

[N152.Ebook] Download PDF Conceiving the Indian Buddhist Patriarchs in China (Kuroda Studies in East Asian Buddhism), by Stuart H. Young

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Conceiving the Indian Buddhist Patriarchs in China (Kuroda Studies in East Asian Buddhism), by Stuart H. Young

Aśvaghoṣa, Nāgārjuna, and Āryadeva are among the most celebrated Indian patriarchs in Asian Buddhist traditions and modern Buddhist studies scholarship. Scholars agree that all three lived in first- to third-century C.E. India, so most studies have focused on locating them in ancient Indian history, religion, or society. To this end, they have used all available accounts of the Indian patriarchs' lives―in Sanskrit, Tibetan, various Central Asian languages, and Chinese, produced over more than a millennium―and viewed them as bearing exclusively on ancient India. Of these sources, medieval Chinese hagiographies are by far the earliest and most abundant.

Conceiving the Indian Buddhist Patriarchs in China is the first attempt to situate the medieval Chinese hagiographies of Aśvaghoṣa, Nāgārjuna, and Āryadeva in the context of Chinese religion, culture, and society of the time. It examines these sources not as windows into ancient Indian history but as valuable records of medieval Chinese efforts to define models of Buddhist sanctity. It explores broader questions concerning Chinese conceptions of ancient Indian Buddhism and concerns about being Buddhist in latter-day China. By propagating the tales and texts of Aśvaghoṣa, Nāgārjuna, and Āryadeva, leaders of the Chinese sangha sought to demonstrate that the means and media of Indian Buddhist enlightenment were readily available in China and that local Chinese adepts could thereby rise to the ranks of the most exalted Buddhist saints across the Sino-Indian divide. Chinese authors also aimed to merge their own kingdom with the Buddhist heartland by demonstrating congruency between Indian and Chinese ideals of spiritual attainment. This volume shows, for the first time, how Chinese Buddhists adduced the patriarchs as evidence that Buddhist masters from ancient India had instantiated the same ideals, practices, and powers expected of all Chinese holy beings and that the expressly foreign religion of Buddhism was thus the best means to sainthood and salvation for latter-day China.

Rich in information and details about the inner world of medieval Chinese Buddhists, Conceiving the Indian Buddhist Patriarchs in China will be welcomed by scholars and students in the fields of Buddhist studies, religious studies, and China studies.

  • Sales Rank: #2643766 in Books
  • Published on: 2015-02-28
  • Released on: 2015-02-28
  • Original language: English
  • Number of items: 1
  • Dimensions: 9.10" h x 1.10" w x 6.10" l, 1.55 pounds
  • Binding: Hardcover
  • 352 pages

Review
. . . this monograph by Stuart H. Young stands out based on the importance of the topic as well as its overall quality. He fills a crucial gap in scholarly studies on Chinese Buddhism. . . . The texts are presented in a philologically sound way (including the Chinese text portions!), with a quality of translations going far beyond the average level usually encountered in the treatment of Chinese Buddhist textual material in Western scholarly publications. (H-Buddhism)

About the Author
Stuart H. Young is assistant professor of East Asian religions in the Department of Religious Studies at Bucknell University.

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Senin, 25 April 2011

[M587.Ebook] Free PDF Lesikar's Business Communication, by NA

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Lesikar's Business Communication, by NA

This 13th edition of Lesikar's Business Communication: Connecting in a Digital World, by Kathryn Rentz, and Paula Lentz brings the contemporary perspective of two expert teachers to Ray Lesikar's classic textbook. Taking a unique problem-solving approach, it integrates current technologies and trends throughout, while maintaining an emphasis on the fundamentals: careful analysis of the communication problem, development of an audience-focused solution, and clear, correct use of language and visuals. Combined with abundant realistic examples, exercises, and cases, this approach makes Lesikar one of the most pedagogically effective books in the field.

  • Sales Rank: #298361 in Books
  • Brand: Brand: Mcgraw Hill Higher Education
  • Published on: 2013-03-01
  • Original language: English
  • Dimensions: 10.67" h x .98" w x 8.39" l, 3.11 pounds
  • Binding: Paperback
  • 679 pages
Features
  • Used Book in Good Condition

About the Author

Dr. Paula Lentz is an associate professor and academic program director in the Department of Business Communication at the University of Wisconsin-Eau Claire. She teaches Business Writing and Advanced Business Writing and develops and teaches online communication courses for the University of Wisconsin MBA Consortium program.

Dr. Lentz is particularly interested in qualitative research that explores narratives and organizational cultures, genre theory, and writing a pedagogy in online environments. She has developed numerous online courses and online materials for hybrid and flipped classrooms. In addition, she has published and presented frequently on topics of rhetoric in business communication and continues to do freelance writing, editing, and consulting. Dr. Lentz's professional activities include involvement in the Association for Business Communication, where she chairs the Academic Environment Committee. She received a BA from Coe College, an MA from UW-Eau Claire, and� PhD in Rhetoric and Scientific and Technical Communication from the University of Minnesota.



Associate Professor in the English Department at the University of Cincinnati. She taught her first business writing class as a doctoral student at the University of Illinois in the early 1980s and has been teaching workplace writing ever since. She helped establish the University of Cincinnati’s professional writing program and has served as its coordinator. She has also won the English Department’s teaching award, directed the department’s graduate program, and helped direct the composition program. Dr. Rentz’s affiliation with the Association for Business Communication goes back to her beginnings as a business writing teacher. Dr. Rentz was named the 2008 winner of the Association for Business Communication's (ABC’s) Outstanding Teacher Award. In addition, an article she co-authored in 2007 just won the association’s award for Outstanding Article in the Journal of Business Communication. She has performed many roles for the association, including serving on the board of directors, organizing a conference, and chairing the publications board. She served two terms as an Associate Editor of the Journal of Business Communication and was Interim Editor from 2000–2001, for which she won the Francis W. Weeks Award of Merit. Dr. Rentz has published articles and commentary on pedagogy, genre theory, narrative, and ethics in such journals as Business Communication Quarterly, the Journal of Business Communication, Technical Communication Quarterly, and the Journal of Business and Technical Communication. She has participated in many professional meetings and seminars over the years and is always learning from her colleagues and her students.

Most helpful customer reviews

0 of 0 people found the following review helpful.
I'm still doing good though but this ain't for me
By Harvey
Idk my business class a lil wack this semester and this book hardly helped me. I'm still doing good though but this ain't for me.

0 of 0 people found the following review helpful.
Almost Spanking Brand New
By Keylolo
Since this was my first time renting a book, I was very pleased. The book looked almost spanking brand new! Very informative! Definitions could use a little more wording and understanding. Overall, good book and I would try a rental again!

0 of 0 people found the following review helpful.
This is exactly what I needed and I only buy ...
By Amazon Customer
This is exactly what I needed and I only buy from Amazon because they are the most reliable and the cheapest!

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Minggu, 24 April 2011

[B460.Ebook] Free PDF Mathematical Olympiad Treasures, by Titu Andreescu, Bogdan Enescu

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Mathematical Olympiad Treasures, by Titu Andreescu, Bogdan Enescu

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Mathematical Olympiad Treasures, by Titu Andreescu, Bogdan Enescu

* "Mathematical Olympiad Treasures" aims at building a bridge between ordinary high school exercises and more sophisticated, intricate and abstract concepts and problems in undergraduate mathematics.

* The book contains a stimulating collection of problems in the subjects of algebra, geometry and trigonometry, number theory and combinatorics.

* The problems are clustered by topic into self-contained sections, that begin with elementary facts, followed by a number of carefully selected problems and an extensive discussion of their solutions.

* Should benefit undergraduate students, advanced high school students, instructors, and coaches.

* "Treasures" is similar in structure to "Challenges", but with more emphasis on unconventional examples, essay answers, and creative thinking.

  • Sales Rank: #2399351 in Books
  • Brand: Brand: Birkh�user Boston
  • Published on: 2010-06-02
  • Original language: English
  • Number of items: 1
  • Dimensions: 9.25" h x .56" w x 6.10" l, .75 pounds
  • Binding: Paperback
  • 234 pages
Features
  • Used Book in Good Condition

Review

"I took great pleasure in reading Mathematical Olympiad Treasures, by Titu Andreescu and Bogdan Enescu. This book is the fruit of the prodigious activity of two well-known creators of mathematics problems in various mathematical journals....

Treasures is organized in six chapters. The first three deal with problems from algebra, geometry and trigonometry, number theory and combinatorics. Chapters 4, 5 and 6 give the solutions to problems presented in the first three chapters. In all the chapters, the reader can find numerous challenging problems. All featured solutions are interesting, given in increasing level of difficulty; some of them are real gems that will give great satisfaction to any math lover attempting to solve the problems—or even extend them. I believe strongly that Mathematical Olympiad Treasures will reveal the beauty of mathematics to all students, teachers and all math lovers."�� —MAA Online

"...this is one of a long recent series of challenging secondary math books, coauthored by Dr. Titu Andreescu and published by Birkh�user, a series that has definitely enriched the literature on secondary mathematics - a credit to the coauthor and to the wisdom of the editor."�� —Zentralblatt

From the Back Cover

"Mathematical Olympiad Treasures" aims at building a bridge between ordinary high school exercises and more sophisticated, intricate and abstract concepts and problems in undergraduate mathematics. The book contains a stimulating collection of problems in the subjects of algebra, geometry and trigonometry, number theory and combinatorics.�While it may be considered a sequel to "Mathematical Olympiad Challenges," the focus of "Treasures" is on engaging a wider audience of undergraduates to think creatively in applying techniques and strategies to problems in the real world.

The problems are clustered by topic into self-contained sections. Unlike "Challenges," however, "Treasures" begins with elementary facts, followed by a number of carefully selected problems and an extensive discussion of their solutions. This discussion then leads to more complicated and more intellectually challenging problems, as well as their solutions. Throughout the book students are encouraged to express their ideas, conjectures, and conclusions in writing. The goal is to help readers develop a host of new mathematical tools and strategies that will be useful beyond the classroom and in a number of disciplines.

"Mathematical Olympiad Treasures" reflects the depth of experience of two seasoned professors and coaches from the United States and Romanian Olympiad teams.

About the Author
Andreescu, Titu, Enescu, Bogdan

Most helpful customer reviews

16 of 18 people found the following review helpful.
Helpful for the experience, but not beginners
By Math_Kid_25
I would recommend this book if you have already developed a repretoire for solving olympiad (USAMO, IMO, etc) level problems. This book teaches a couple more interesting startegies to add to your olympiad bag of tricks. However, a beginner to olympiad problems may wish to consider a different book first.

I bought this book this year before my first USAMO. I wanted to acquaint myself with important problem solving techniques I would need for this test. Whiel this book provided many important insights and tricks, It was not helpful for my purposes. Basically, it gave plenty of extra tricks, but very, very little on where to apply these tricks and how a student would know to use a given technique.

In all, I'd rate this book a 5 for advanced problem solvers who know what they are doing but want a good set of problems and extra techniques. However, a newcomer to olympiads may wish to consider a different book to start educating themselves in problem-solving

13 of 15 people found the following review helpful.
Definitely a treasure!
By SCK
Andreescu delivered again! This book teaches powerful math problem solving techniques through a series of graded problems. The insight from these two renounced problem solvers of elementary problems at the olympiad level is prevalent throughout the book, which is what makes this book a treasure. You'll learn wonderful techniques and come away with a satisfying feeling after you can solve some of the problems that seem impossible to you before. I hope these authors continue to put out such gems in the near future. Enjoy!

4 of 4 people found the following review helpful.
A good pedagogical aid for math competition
By M. Wang
This is a great compilation of various subjects in math from which quiz problems often stem. The thought process for solving a particular type of quizzes is illustrated with actual sample problems, as it should be. I think it will be perfect for my son when he gets a little older, but this book may be too easy for adults. I purchased it after enjoying months of puzzle-solving pleasure on my long daily train rides with "Mathematical Olympiad Challenges" from the same authors, but this book poses so little challenge that there is virtually no risk of stumbling over any problem. The authors acknowledge the difference in difficulty levels in the promotional literature. Perhaps they will publish a collection of harder problems separately.

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Sabtu, 23 April 2011

[K207.Ebook] Free PDF How Do I Love Me?, by Helen M Johnson

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How Do I Love Me?, by Helen M Johnson

This excellent book on self-esteem grew out of the author's many years of successfully teaching people of all ages and walks of life how to aquire a high level of self-esteem and how to keep it. Ms. Johnson's experiences as an elementary school teacher, high school and college counselor, lecturer, consultant and workshop leader have been drawn upon to develop this readable and practical "how to" book on self-esteem.

  • Sales Rank: #5227947 in Books
  • Published on: 1986-12
  • Number of items: 1
  • Dimensions: 9.00" h x 6.00" w x .25" l,
  • Binding: Paperback
  • 105 pages

From the Publisher
Helen Johnson's How Do I Love Me? has helped many thousands of people of all ages and walks of life to acquire and keep a high level of self-esteem. Now in the third edition, Ms. Johnson's book has been updated and fine-tuned to bring new hope to many more in the years to come.

If You:

concentrate on your weaknesses fear trying something new lie awake agonizing about what you've done or said hesitate to express your thoughts in a group worry about what people think of you

feel inadequate and unsure of yourself often think you are to blame when things go wrong live by others' values spend precious time with destructive people disappoint yourself by not reaching your goals expect to be perfect blame your parents for your low self-esteem

This book can help you to feel capable, worthy, significant, loveable, and help you to find high self-esteem!

From the Author
In both the individual counseling I do and in the classes I teach, I find that a simple, specific, step-by-step method is needed to find self-esteem. People want explicit directions on how to acquire and keep a positive image of themselves. It did no good for me to assure them that they were okay or have their classmates give them positive feedback. When people feel inadequate, they are not open to verbal strokes from the outside. They need to feel the warmth of positive thoughts from the inside; they need to speak to themselves in an approving manner. They want a system which they can put into action. Over the years, I have developed such a method which has proved to be successful when implemented by hundreds of counselees and students. This step-by-step system has also been presented at the many workshops I have conducted on self-esteem. I have received comments and letters from those in attendance saying that they have applied these techniques to their lives, and it has made a remarkable difference. They have asked me to record these systematic procedures in book form. This book is in response to their requests."

About the Author
Helen M. Johnson’s education includes the following: B.A. from the University of Nebraska with Phi Beta Kappa honors; B.S., M.A. in Education from the University of Minnesota; and M.A. in Counseling from Arizona State University.

She has been an elementary school teacher, co-owner of a children’s clothing shop, a high school counselor, and a counselor at Scottsdale Community College for over twenty years. She is also involved in lecturing, consulting and leading workshops.

Ms. Johnson's other passion is Mountain Bluebirds, about which she has written a book and produced a video.

Most helpful customer reviews

5 of 5 people found the following review helpful.
A must read for anyone that struggles with low self esteem.
By A Customer
This book can help anyone feel better about themselves. It really goes to the heart of low self esteem. It has lots of activities and hints and is easy to read. The world would be a better place if everyone loved themselves a little more.

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Jumat, 22 April 2011

[I784.Ebook] Download Developability of Biotherapeutics: Computational ApproachesFrom CRC Press

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Developability of Biotherapeutics: Computational ApproachesFrom CRC Press

Biopharmaceuticals are emerging as frontline medicines to combat several life-threatening and chronic diseases. However, such medicines are expensive to develop and produce on a commercial scale, contributing to rising healthcare costs. Developability of Biotherapeutics: Computational Approaches describes applications of computational and molecular modeling techniques that improve the overall process of discovery and development by removing empiricism.

The concept of developability involves making rational choices at the pre-clinical stages of biopharmaceutical drug development that could positively impact clinical outcomes. The book also addresses a general lack of awareness of the many different contributions that computation can make to biopharmaceutical drug development.

This informative and practical reference is a valuable resource for professionals engaged in industrial research and development, scientists working with regulatory agencies, and pharmacy, medicine, and life science students and educators. It focuses primarily on the developability of monoclonal antibody candidates, but the principles described can also be extended to other modalities such as recombinant proteins, fusion proteins, antibody drug conjugates and vaccines.

The book is organized into two sections. The first discusses principles and applications of computational approaches toward discovering and developing biopharmaceutical drugs. The second presents best practices in developability assessments of early-stage biopharmaceutical drug candidates.

In addition to raising awareness of the promise of computational research, this book also discusses solutions required to improve the success rate of translating biologic drug candidates into products available in the clinic. As such, it is a rich source of information on current principles and practices as well as a starting point for finding innovative applications of computation towards biopharmaceutical drug development.

  • Sales Rank: #3276076 in Books
  • Published on: 2015-12-14
  • Original language: English
  • Number of items: 1
  • Dimensions: 9.20" h x .90" w x 6.20" l, .0 pounds
  • Binding: Hardcover
  • 315 pages

Review

‘Developability of Biotherapeutics: Computational Approaches presents the most extensive and systematic overview to date, of modern computational approaches that are being used industrially to assess potential manufacturability and overall ease of development of biotherapeutics such as monoclonal antibodies. The book covers a wide array of topics, spanning from immunogenicity and pharmacokinetic/dynamic properties to key chemical and physical stability attributes. It is recommended as important reading for researchers from both academic and industrial perspectives, and will be of particular interest for graduate students seeking to gain an experienced perspective of the current state of the art and opportunities for high impact research in the future’.

– Christopher J. Roberts, Professor of Chemical & Biomolecular Engineering, University of Delaware.

About the Author

Sandeep Kumar, PhD, is a senior principal scientist at Pfizer, Inc. in the Biotherapeutics Pharmaceutical Sciences group, working on computational modeling and developability risk assessments of a wide variety of biotherapeutic drug candidates, including monoclonal antibodies, antibody-based therapeutics, fusion proteins, vaccines, and antibody–drug conjugates. He earned his PhD in computational biophysics from the Molecular Biophysics Unit of the Indian Institute of Science, Bangalore, India, and performed postdoctoral research on proteins at the National Cancer Institute in Frederick, Maryland, a part of the National Institutes of Health. He has been an assistant professor (research-track) at Georgetown University Medical Center, Washington, DC; an assistant professor at the Indian Institute of Technology, Kanpur; and an associate research scientist at Johns Hopkins University, Baltimore, Maryland. He has more than 17 years of experience in computational protein sciences. He has contributed more than 60 research papers, review articles, and book chapters, has delivered more than 40 invited talks, and has chaired sessions of several conferences. He has won several fellowships and awards, including a Fogarty visiting scientist fellowship at NIH and the 2014 Ebert Prize from the American Pharmacists Association. He has also mentored several graduate students and postdoctoral scientists.

Satish Kumar Singh, PhD, is a research fellow at Pfizer, Inc. in the Biotherapeutics Pharmaceutical Sciences group, and an adjunct professor of the Department of Physical Pharmaceutical Chemistry at Uppsala University in Sweden. His responsibilities include leading formulation, product, and process development activities for biologics and therapeutic vaccines. He earned his PhD in chemical engineering from Kansas State University. He has more than 25 years of industrial experience and has published more than 50 peer-reviewed articles with emphasis on the colloidal and physical chemistry of macromolecules. He also holds four patents. He is involved in several professional groups through the American Association of Pharmaceutical Scientists and the USP, was chair of the Protein Aggregation and Immunogenicity Focus group, and is a frequently invited speaker at various conferences and symposia.

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0 of 0 people found the following review helpful.
A very dense, but very readable (and nicely visual) book on biopharmaceuticals
By Boris
Excellent text on developability. This book is surprising in the breadth and depth that it covers, especially on improving a business' odds of success and de-risking the biologics pipeline. An excellent list of top-flight authors take on the chapters.

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Developability of Biotherapeutics: Computational ApproachesFrom CRC Press PDF

Developability of Biotherapeutics: Computational ApproachesFrom CRC Press PDF

Developability of Biotherapeutics: Computational ApproachesFrom CRC Press PDF
Developability of Biotherapeutics: Computational ApproachesFrom CRC Press PDF